HIV/AIDS News

BOSTON — Five-year post-trial data indicated male circumcision reduced more than half of all new HIV infections when compared with uncircumcised men in Uganda. Yet, surveillance suggested an increase in "risky sexual behaviors" among both circumcised and uncircumcised men, according to Xiangrong Kong, PhD.

BOSTON – The use of a down-referral strategy from higher- to lower-level health care facilities and staff reduced costs and improved outcomes for patients on antiretroviral therapy in Johannesburg, South Africa.

Children in developing countries were older at the time of HIV diagnosis with more advanced stages of disease than children in developed countries. Continued improvement of interventions, including nutritional support and treating and preventing coinfections, may help improve survival rates in RLCs, according to researchers from the University of Washington in Seattle.

WHO researchers recommend triple-antiretroviral prophylaxis — as opposed to the standard regimen — after finding that it reduced the risk for HIV-1 transmission from mother-to-child during nursing by as much as 53%.

VANCOUVER — Less than 70% of children with HIV achieved seroprotection from the AS03-adjuvanted pandemic influenza A (H1N1) vaccine (Arepanrix, GlaxoSmithKline), according to findings presented at the 48th Annual Meeting of the Infectious Diseases Society of America.

VANCOUVER – HIV may be playing a role in recent outbreaks of measles in sub-Saharan Africa, according to findings presented at the 48th Annual Meeting of the Infectious Diseases Society of America.

VANCOUVER — The p21 host protein that inhibits HIV replication in hematopoietic stem cells appeared to restrict HIV infection in elite controllers. Manipulation of p21 may offer opportunities to increase hosts’ resistance to HIV infection, according to new findings presented by Mathias Lichterfeld, MD, PhD.

Women with HIV who have prior exposure to single-dose nevirapine may be treated more effectively at treatment initiation with a lopinavir-based antiretroviral therapy regimen than with a nevirapine-based regimen, according to study results.

A full-dose regimen of stavudine, lamivudine and nevirapine was linked to high rates of rash but only a 12% rate of clinical toxicity, according to study results.

Women with HIV who take vitamin A and beta carotene may be significantly more likely to transmit the infection to their infants than women not taking those vitamins, according to recent study findings. Results of a companion study indicated that women taking vitamin supplements may be at increased risk for subclinical mastitis.