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Vitamin D deficiency associated with tear hyperosmolarity, dysfunction
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A single center study demonstrated that patients with vitamin D deficiency should be further evaluated if they have syndromes causing dry eye and that dry eye patients be tested for vitamin D deficiency.
The study comprised two groups: 60 eyes of 30 patients with vitamin D deficiency in group 1 and 60 eyes of 30 healthy individuals in group 2.
All patients were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer’s 1 test, tear break-up time, scoring of ocular surface fluorescein staining using a modified Oxford scale and tear osmolarity.
Mean tear osmolarity was significantly higher in group 1 compared with group 2, according to the study.
The mean superficial punctate staining, as measured by the Oxford scale, differed significantly between group 1 and group 2. The mean OSDI scores were significantly higher in group 1 compared with group 2.
Vitamin D is a multifunctional hormone that plays an important role in ocular health, the researchers wrote. – by Abigail Sutton
Disclosure: The researchers reported no relevant financial disclosures.
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