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Researchers: Contact lens wear may be risk factor for MGD
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The mucocutaneous junction has an effect on comfort upon insertion, comfort after 5 minutes, end-of-day comfort and ability to obtain ocular moisture in contact lens wearers, according to a study in Optometry and Vision Science.
Researchers also found meibomian gland expressibility had a significant effect on general comfort, comfort throughout the day and the ability to maintain ocular moisture.
Cox and colleagues studied 23 subjects (67.5% female) with a mean age of 30.3 years.
Orifice pouting/plugging, compromised meibomian gland (MG) expressibility and lid margin vascularity were commonly observed throughout the patients, according to researchers.
Patient age had an effect on wear time, comfort upon insertion, end-of-day comfort, comfort throughout the day, the ability to maintain ocular moisture, burning eyes and stinging eyes in both the mucocutaneous junction (MCJ) displacement and MG expressibility models, according to the study.
Vascularity of the eyelid margin was a common finding in this study, which may suggest an inflammatory component to contact lens wear, according to the researchers.
“The presence of pouting/plugging and compromised MG expressibility were also common and are signs of meibomian gland dysfunction (MGD), which supports that contact lens wear may be a risk factor for MGD,” they wrote.
The researchers concluded that subjects with compromised MG expressibility have decreased comfort compared to those without the compromise. – by Abigail Sutton
Disclosure: The study was funded by Johnson & Johnson Vision Care Inc.
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