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Addition of pigment to etafilcon A lenses has no effect on corneal physiology
Researchers determined that the addition of polyvinyl pyrrolidone or pigments to etafilcon A to obtain a limbal ring design have no impact on corneal swelling or limbal/bulbar hyperemia during normal open-eye wear.
Moezzi and colleagues reported in Optometry and Vision Science that they conducted the partial double-masked, randomized, bilateral crossover study in 24 Asian subjects, comparing Johnson & Johnson Vision Care’s 1-Day Acuvue Define (AD) to AD with Lacreon (ADL), no lens wear and a control lens with no tint (1-Day Acuvue Moist).
After 8 hours of open-eye wear, central corneal swelling with all lens wear measured by either optical pachymeter or OCT methods was negligible, according to researchers.
Peripheral corneal swelling least-square mean differences with OCT were -0.03% and -0.26% among AD and ADL and the control lens, respectively, and 1.67% and 1.45% among AD and ADL and no lens wear, respectively.
d no endothelial blebs.
“All three study lenses can, therefore, be interchangeably used for open-eye daily disposable wear, with the anticipation of minimal physiological difference from no lens wear,” the researchers concluded.
“These results confirm that the addition of polyvinyl pyrrolidone or pigments to etafilcon A to obtain a limbal ring design have no impact on corneal swelling or limbal/bulbar hyperemia during normal open-eye wear,” they added. – by Abigail Sutton
Disclosure: Moezzi reported no relevant financial disclosures. Please see the full study for all remaining authors’ financial disclosures.