March 03, 2016
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Miniscleral contacts induce minimal corneal swelling over 8 hours of wear

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Modern high Dk miniscleral contact lenses do not cause clinically significant corneal edema after 8 hours of lens wear in young healthy participants with normal corneas, according to research in Optometry and Vision Science.

A small, but significant amount of edema was observed after 8 hours of miniscleral lens wear; however, the mean was well within the magnitude of physiological corneal swelling associated with overnight eyelid closure, according to the study.

Vincent and colleagues looked at 15 young healthy adult subjects between 18 and 32 years with a visual acuity of 0.00 logMAR or better.

The subjects wore the miniscleral contact lens in their left eye, with measurements taken before insertion, between 8 a.m. and 10 a.m. and immediately after removal at 8 hours of wear, between 4 p.m. and 6 p.m.

After 8 hours of wear, corneal swelling was, on average, less than 2%, according to the researchers. The mean increase in corneal thickness over the central 6 mm was 10.23 ± 5.77 µm, which did not vary significantly between the central 0 to 3 mm of the cornea or the peripheral region.

Overnight eyelid closure induces approximately 4% of physiological edema, according to the study.

“Greater changes in corneal edema may be apparent following longer periods of lens wear or in patients with compromised or older corneas with reduced endothelial function, which requires further investigation,” the researchers wrote. – by Abigail Sutton

Disclosure: The researchers reported no relevant financial disclosures.