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Pharmacological agents offer most effective myopia control
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High-dose, moderate-dose and low-dose atropine showed the best control of myopia progression, according to a study recently published in Ophthalmology.
In their meta-analysis of 30 randomized control trials, Huang and colleagues also concluded that pirenzepine, orthokeratology, peripheral defocus modifying contact lenses, cyclopentolate and prismatic bifocal spectacle lenses showed moderate effects in myopia progression.
Progressive-addition spectacle lenses, bifocal spectacle lenses, peripheral defocus modifying spectacle lenses and more outdoor activities resulted in weak effects, according to the researchers. Gas-permeable contact lenses, soft contact lenses, undercorrected single vision spectacle lenses and timolol were ineffective.
In addition, Asian children benefited more from treatment than Caucasian children, and most interventions lose their early effect in the second year, based on the study results.
The researchers concluded that low-dose atropine, pirenzepine and soft contact lenses with myopia control features are the best options for managing myopia progression. – by Abigail Sutton
Disclosure: The researchers reported no relevant financial disclosures.
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