August 07, 2015
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OCT identifies lacrimal gland components

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Optical coherence tomography may prove useful in examining lacrimal glands in dry eye patients, according to a study recently published in Ophthalmology.

Doh and colleagues conducted a study of 122 subjects, including 67 dry eye patients, to assess the use of OCT technology.

Using the Heidelberg OCT (Spectralis, Heidelberg), researchers were able to identify the interlobular ducts, excretory ducts, intralobular ducts, parenchyma, acini and lobules in the lacrimal gland by using cross-sectional photographs.

Researchers noted that they were unable to determine OCT parameters that differentiated healthy patients from dry eye patients.

"However, further development of the technology will allow for evaluation of the lacrimal gland without biopsy in vivo," they concluded. "This will greatly facilitate studies of changes in the lacrimal glands in dry eye syndrome, such as Sjögren’s syndrome and ocular graft-versus-host disease." – by Chelsea Frajerman Pardes

Disclosures: The authors reported no relevant financial disclosures.