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No association between objective, subjective parameters for dry eye assessment
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No association was found between clinical signs and a patient's symptoms when evaluating for dry eye syndrome, researchers reported in Investigational Ophthalmology and Visual Science.
Schmidl and colleagues conducted a cross-sectional study in which they assessed 52 patients with dry eye syndrome.
In order to assess clinical parameters, the researchers measured tear osmolarity, ocular scattering index, tear break-up time, corneal fluorescein staining and tear film thickness, which involved a custom-built ultrahigh-resolution Fourier-domain OCT.
To assess symptoms, the researchers utilized the Ocular Surface Disease Index.
Results showed that the Ocular Surface Disease Index was significantly negatively correlated with tear film thickness, but no other evaluated signs.
"Our data support the results of several other authors that, in general, the association between signs and symptoms is weak in patients with dry eye syndrome," the authors concluded. "Tear film thickness was the only variable that correlated with an objective and subjective parameter for the assessment of dry eye syndrome. Measurement of tear film thickness with OCT, therefore, might become a valuable tool in the diagnosis and monitoring of dry eye syndrome in the future." – by Chelsea Frajerman
Disclosure: The authors report no relevant financial interests.
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