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Ortho-K may slow myopia progression in children
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Orthokeratology may be successful in slowing the progression of myopia in children, according to a study recently published in Optometry and Vision Science.
Si and colleagues conducted a literature search and meta-analysis to evaluate previous studies that had assessed the treatment.
Researchers utilized PubMed, the Cochrane Library and Embase to locate relevant literature and the Jadad score to grade the quality of the literature.
Ultimately, the authors utilized seven studies in their meta-analysis – five nonrandomized controlled trials and two randomized controlled trials. Altogether, the seven studies included 435 participants split into 218 ortho-K participants and 217 control group participants. The participants were 6 to 16 years old.
Results showed that ortho-K participants demonstrated a reduction of axial length elongation and vitreous chamber depth (VCD) elongation.
"The major purpose of the present meta-analysis was to evaluate the efficacy of orthokeratology in myopia control," the authors wrote. "Our meta-analysis suggests that compared with control, orthokeratology may effectively reduce the elongation of axial length to a certain extent, with mean differences of -0.26 mm in 2 years.
“Moreover, the difference between orthokeratology and control in VCD elongation was -0.18 mm in 2 years,” they continued. “Exclusion of any single study and sensitivity analysis based on various exclusion criteria did not materially alter the pooled results, which added robustness to our main result."
Disclosure: The authors reported no financial disclosures.
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