March 07, 2014
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Acucela enrolls patients in trial for oral AMD agent

Acucela Inc. announced that it has completed enrollment in its ongoing phase 2b/3 clinical trial investigating the oral agent, emixustat, in subjects with geographic atrophy.

The Safety and Efficacy Assessment Treatment Trials of Emixustat HCl (SEATTLE) study is a multicenter, randomized, double-masked, dose-ranging trial initiated in early 2013, the company reported in a press release.

Emixustat is being studied in 508 patients with geographic atrophy associated with dry age-related macular degeneration to determine if the agent slows the rate of progression of geographic atrophy lesions, the company reported.

“Completing enrollment in this trial ahead of schedule represents a tremendous achievement for the program,” Ryo Kubota, MD, PhD, Acucela chairman, president and CEO, stated in the release.