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Adverse event rates, comfort ratings have no correlation, study says
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A study reporting on the effect of various contact lenses and lens care solution combinations on comfort and adverse events found that those pairings receiving the best comfort ratings did not necessarily have a favorable adverse event rate.
The retrospective analysis included 40 participants and 28 lens-solution combinations. Participants were assigned combinations on a daily wear basis and were seen at baseline, 2 weeks, 1 month and 3 months.
The overall adverse event (AE) rate was 3.6 events per 100 participant-months. AE rate was found to be lower in daily disposables compared with that in daily wear lenses (3.1% vs. 10.9%; P < .001).
The study was unable to determine any significant correlations between overall AE rates and comfort on insertion or at end of day, and less than 18% of the combinations tested combined good comfort with low AE rates.
“Both subjective comfort responses and AE rates varied according to the combination of lens type and care system in use,” the study authors said. “Practitioners can maximize behavior with respect to both these factors by choosing an appropriate care system for the lenses they prescribe.”
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