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Study finds LASIK has no effect on spectral domain OCT measurements
BOSTON — Researchers reported here at Academy 2011 Boston that retinal nerve fiber layer and ganglion cell complex measurements obtained by spectral domain ocular coherence tomography were not significantly affected by LASIK.
"Previous studies found alteration of retinal nerve fiber layer (RNFL) after refractive surgeries as measured by scanning laser polarimetry but not from OCT. The resolution of time domain OCT was 10 µm while spectral domain OCT used nowadays has a resolution of up to 4 µm," Andrew K.C. Lam, PhD, and colleagues reported in the poster.
According to the study abstract, 52 eyes from 26 young adults were included in the study. There was a mean reduction in myopia from -6.16 D to -0.188 D as a result of LASIK, as well as a reduction in central corneal thickness from 542.6 µm to 423.8 µm.
No significant change in RNFL was seen at day 1.
"Although more myopic correction had a greater thickening effect on the measured RNFL, the association was not significant," Dr. Lam and colleagues reported.
One-month results obtained from 19 subjects showed no significant difference in RNFL, they said.
"Using SD-OCT, no significant change was found in retinal nerve fiber layer and ganglion cell complex measurements before and after LASIK," the researchers reported. "However, variation of superior RNFL was reaching significance. It was mainly due to thinner RNFL 1 month post-LASIK."