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Corneal thickness, IOP higher in aphakic eyes of children

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Corneal thickness measurements in the aphakic eyes of pediatric patients were significantly higher than the measurements in their phakic fellow eyes, a study found. The finding may be helpful in interpreting IOP measurements in pediatric patients, the researchers said.

John W. Simon, MD, and colleagues at the Lions Eye Institute in Albany, N.Y., measured the central corneal thickness (CCT), IOP and optic nerve cupping in patients from the practices of two pediatric ophthalmologists and two glaucoma specialists.

In 36 aphakic eyes and six pseudophakic eyes, CCT averaged 660 µm, compared with 576 µm in the patients’ phakic fellow eyes. Glaucoma (defined as an IOP of at least 35 mm Hg or an IOP of at least 22 mm Hg associated with optic nerve changes) occurred in 21% of 28 aphakic eyes but in none of the pseudophakic eyes.

The study is published in the August issue of the Journal of American Association for Pediatric Ophthalmology and Strabismus.