Fellow eye rhegmatogenous retinal detachment risk higher in men, active smokers
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CHICAGO — Men, active smokers and those with a younger age at diagnosis of rhegmatogenous retinal detachment in one eye were factors associated with a higher risk for developing detachment in the other eye, according to a study.
“Rhegmatogenous retinal detachment is a sight-threatening condition, and patients who have developed an RRD in one eye often ask what is the chance their fellow eye may be affected,” William Kearney, MS, and colleagues wrote in a poster presentation at the American Academy of Ophthalmology meeting.
Using the AAO IRIS Registry, Kearney and colleagues performed a retrospective cohort analysis of 212,886 patients (61.3% men, 38.7% women; mean age, 60.7 years) who received a new rhegmatogenous retinal detachment (RRD) diagnosis between 2016 and 2020 to investigate the rate of RRD in the fellow eye and potential factors that may contribute to it.
In the study, 3.2% of patients developed RRD in the fellow eye within a mean of 406.5 days after the first RRD. Patients who were men (P < .001), who were active smokers (P = .004) or who had a younger age at the time of the first diagnosis (P < .001) had a higher risk for RRD in the fellow eye.
Additionally, patients who were Asian or Black had a higher risk for RRD in the fellow eye compared with white patients (P < .001 for both). Patients from the Northeast region were more likely to experience a second RRD compared with those from the Midwest (P = .007).
The study said 57.9% of patients underwent pars plana vitrectomy as an initial treatment procedure, with 10.7% of patients requiring two procedures or more.
“Identifying fellow eyes with an increased risk of RRD could help improve our ability to diagnose RRDs earlier, which is essential since early repair increases the success rate of retinal reattachment surgery and improves the visual outcomes,” Kearney and colleagues wrote.
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Kearney W, et al. Fellow eye risk of rhegmatogenous retinal detachment: An AAO IRIS Registry analysis. Presented at: American Academy of Ophthalmology meeting; Sept. 30-Oct. 3, 2022; Chicago.
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