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December 02, 2020
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Janssen acquires rights for geographic atrophy gene therapy

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Janssen Pharmaceuticals has acquired the rights to HMR59, an investigational one-time intravitreal injection gene therapy being developed for the treatment of geographic atrophy, from Hemera Biosciences, according to a press release.

The therapy is intended to increase the ability of retina cells to make a soluble form of CD59, a protein that protects the retina from damage, thereby preventing damage and saving sight, the release said.

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A phase 1 study of the therapy in geographic atrophy is complete, with a second phase 1 study in wet age-related macular degeneration underway.

“With the potential to transform how AMD is managed, HMR59 fulfills a key area of focus for Janssen, widens the company’s focus to more common eye diseases and serves as an important driver for long-term company growth,” James F. List, MD, PhD, global therapeutic area head, cardiovascular and metabolism, Janssen Research and Development, told Healio/OSN.

Financial details of the acquisition were not disclosed.