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Wet Age-Related Macular Degeneration

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May 16, 2025
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VIDEO: Subcutaneous injection shows promise for wet AMD, DME

FORT LAUDERDALE, Fla. — In this Healio Video Perspective, Michael A. Singer, MD, discusses promising results for migaldendranib for the treatment of wet age-related macular degeneration and diabetic macular edema.

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May 13, 2025
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Aflibercept 8 mg shows sustained improvements in wet AMD through 156 weeks

FORT LAUDERDALE, Fla. — Aflibercept 8 mg demonstrated sustained functional and anatomic improvements in patients with wet age-related macular degeneration through 156 weeks, according to a presenter.

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April 21, 2025
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FDA does not approve additional extended dosing intervals for Eylea HD

  The FDA issued a complete response letter for a supplemental biologics license application, in which it did not approve extending the dosing intervals for Eylea HD, according to a press release from Regeneron.

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April 15, 2025
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Are new anti-VEGF agents beneficial for pigment epithelial detachment?

SEVILLE, Spain — Retinal pigment epithelial detachment is associated with neovascular age-related macular degeneration in 30% to 80% of cases, according to the literature.

Clinical Guidance
Geographic Atrophy
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David A Eichenbaum, MD, FASRS

Free clinical reference tool that includes treatment options, diagnosis information, guidelines and more.

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March 31, 2025
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Opthea discontinues development of sozinibercept in wet AMD

Opthea has discontinued development of sozinibercept in wet age-related macular degeneration, according to a press release.

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March 24, 2025
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Phase 3 COAST trial of wet AMD combination therapy misses primary endpoint

  The phase 3 COAST trial investigating 2 mg sozinibercept for the treatment of wet age-related macular degeneration in combination with 2 mg aflibercept did not meet its primary endpoint, according to a press release from Opthea.

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February 11, 2025
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VIDEO: EYP-1901 shows noninferiority to aflibercept in wet AMD

KOLOA, Hawaii — In this Healio Video Perspective from Retina 2025, Ashkan M. Abbey, MD, discusses 1-year results from the phase 2 DAVIO 2 clinical trial investigating EYP-1901 in previously treated wet age-related macular degeneration.

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January 29, 2025
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VIDEO: Duravyu for wet AMD shows similar outcomes to aflibercept

KOLOA, Hawaii — In this Healio Video Perspective from Retina 2025, Ramiro Ribeiro, MD, PhD, of EyePoint Pharmaceuticals, discusses Duravyu, a vorolanib intravitreal insert.

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