Nutritional risk may be linked to infection-, not cardiovascular-related, hospitalizations
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Key takeaways:
- In the study, 566 patients had cardiovascular disease-related hospitalization during 2.6 years.
- Meanwhile, 375 patients experienced infection-related hospitalization during the same period.
Higher nutritional risk may be associated with infection-related hospitalization but not cardiovascular disease-related hospitalization in patients on dialysis, according to results of a prospective study.
“Therefore, prevention of hospitalization in patients undergoing dialysis is critical to both improving poor outcomes and reducing medical costs,” Katsuhito Mori, MD, PhD, of the Osaka Metropolitan University Graduate School of Medicine in Japan, wrote with colleagues. “To date, however, no implementable countermeasures in these patients have yet been taken.”
Researchers used data from the Japanese Dialysis Outcomes and Practice Pattern Study to find whether nutritional disorder was linked to hospitalization and death in patients on maintenance hemodialysis. Overall, 4,021 patients were included in the study and categorized into low-, medium- and high-risk groups.
Main outcomes were cardiovascular disease-related or infection-related hospitalization.
Of the included patients, 566 had cardiovascular disease-related hospitalization and 375 experienced infection-related hospitalization during a median follow-up of 2.6 years.
Researchers found that at baseline, Nutritional Risk Index for Japanese Hemodialysis (NRI-JH) was linked to infection-related but not cardiovascular-related hospitalization. It was also linked to all-cause mortality, the study showed. Baseline and latest high-risk NRI-JH groups were linked to death after cardiovascular- and infection-related hospitalizations.
“These findings suggest the usefulness of NRI-JH as a nutritional indicator for infectious events in hemodialysis patients,” Mori and colleagues wrote. “In addition, they may be useful in the planning of individual nutritional care to improve outcomes after hospitalization.”
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