Drinking coffee associated with lower risk for chronic kidney disease
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Data included in a meta-analysis published in the Journal of Renal Nutrition show drinking coffee was associated with lower risks for incident chronic kidney disease, end-stage kidney disease, albuminuria and related mortality.
“Coffee is one of the most consumed beverages worldwide and is generally considered safe for CKD patients, although a number of caveats may limit its consumption (potassium contents, phosphate from milk or additives, amount of fluid, acute pressor effect),” Mehmet Kanbay, MD, and colleagues wrote. “As it is the case for items with widespread consumption, minimal effects may have significant population-wide health consequences.”
Kanbay and colleagues searched PubMed, Web of Science, Embase and the Cochrane Central Register of Controlled Trials for studies that addressed coffee and CKD using a cross-sectional, retrospective or prospective design and were published in a peer-reviewed journal until February 2020. They pooled study HRs and ORs using the random-effects model.
Final analysis included results from seven cohort and five cross-sectional studies that evaluated a total of 505,841 patients. Data showed drinking coffee was linked to decreased risks for CKD (RR=0.86; 95% CI, 0.76-0.97), ESKD (HR = 0.82; 95% CI, 0.72-0.94) and albuminuria (OR = 0.81; 95% CI, 0.54-0.96). Risk for CKD-related mortality was lower for coffee drinkers (HR = 0.72; 95% CI, 0.54-0.96). Researchers wrote that people who drank two or more cups of coffee per day had a lower risk compared with people who drank one or fewer cups.
“Future prospective, multicenter, well-designed studies are warranted to formally evaluate the impact of coffee consumption on renal outcomes,” researchers wrote, noting that one limitation of the meta-analysis methodology was quality variation between studies.
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