Gastrointestinal Cancer News

Sociodemographic factors may contribute to disparities in testing for two key biomarkers among patients with metastatic colorectal cancer, according to study results.

Older adult cancer survivors who were overweight or obese at the time of first primary cancer diagnosis had a higher risk for developing second cancers, according to findings presented at ASCO Annual Meeting.

The FDA has approved Guardant Health’s Shield blood test to screen for colorectal cancer in patients aged 45 years and older at average risk for disease, according to a company press release.

Surveillance of individuals at a high risk for pancreatic ductal adenocarcinoma led to the detection of smaller, earlier-stage tumors, according to results of a comparative cohort study.

Autonomous AI exhibited “noninferior accuracy” for optical diagnosis of diminutive colorectal polyps vs. AI-assisted endoscopists, yet surpassed endoscopist accuracy in later pathology-based surveillance intervals, according to researchers.

A novel immunotherapy approach for solid, epithelial cancers reduced tumor burden among multiple patients with metastatic colon cancer, according to phase 2 study results.

Remaining current on screening for hepatocellular carcinoma correlated with a “survival benefit” in older adults with hepatitis C virus-related cirrhosis who achieved viral cure but later developed HCC, according to researchers.

In a dose-dependent manner, fazirsiran reduced serum and liver concentrations of Z-AAT and also improved histological measures in patients with homozygous ZZ alpha-1 antitrypsin deficiency-associated liver disease, according to data.

Editor’s note: This is the fourth in a series of five stories from ASCO Voices, a session during ASCO Annual Meeting focused on the human side of oncology.

Treatment with Dupixent led to histologic remission at week 16 among a greater percentage of pediatric patients with eosinophilic esophagitis refractory to proton-pump inhibitor therapy compared with placebo, according to study results.