Gastrointestinal Cancer News

Neoadjuvant chemoradiotherpy followed by transanal endoscopic microsurgery may be a viable alternative to conventional total mesorectal excision for patients with early-stage rectal cancer, according to results of a phase 2 feasibility study.

Consuming high amounts of dietary fiber and whole grains was associated with reduced risk for noncommunicable diseases, such as coronary heart disease, type 2 diabetes and colorectal cancer, according to findings published in The Lancet.

Patients with cancer and comorbidities are routinely left out of clinical trial discussions, offers and participation, according to results of a study published in JAMA Oncology.

A randomized phase 3 trial designed to compare nivolumab with chemotherapy for patients with unresectable advanced or recurrent esophageal cancer met its primary endpoint of OS, according to a company-issued press release.

On Nov. 26, the FDA announced the accelerated approval of larotrectinib as the first small molecule inhibitor for use in a “cancer-agnostic” manner, in pediatric and adult human cancers that harbor neurotrophic receptor tyrosine kinase gene fusions.

Patients with esophageal cancer who underwent a hybrid minimally invasive esophagectomy had a lower incidence of intraoperative and postoperative major complications than patients who underwent open surgery, according to results of a randomized, phase 3 trial published in The New England Journal of Medicine.

The overall rate of cancer deaths in the U.S. has declined by 27% during the past 25 years, with approximately 2.6 million fewer cancer deaths reported between 1991 and 2016, according to data from Cancer Statistics 2019, American Cancer Society’s annual report on cancer rates and trends.

The risk for suicide among patients with cancer rises significantly in the first year after diagnosis compared with the general population, according to a retrospective study published in Cancer.

Patients with frequent cases of basal cell carcinoma appeared to be at three times greater risk for developing other unrelated cancers, including blood, breast, colon and prostate cancers, according to study findings.

The FDA granted fast track designation to ONM-100, an IV intraoperative imaging agent used to detect tumors and metastatic lymph nodes during surgery of solid cancers.