Gastrointestinal Cancer News

Maintenance chemotherapy following initial treatment appeared to be more beneficial for patients with metastatic colorectal cancer than continuing a full induction regimen until disease progression, according to results of a meta-analysis of randomized clinical trials published in JAMA Oncology.

A risk score built from nearly 100 genetic variants commonly associated with colorectal cancer may help identify younger individuals who would benefit the most from preventive measures and early screening, according to research published in Gastroenterology.

The Affordable Care Act’s dependent coverage expansion provision has resulted in earlier-stage diagnosis and more timely receipt of adjuvant chemotherapy among young patients with colorectal cancer, according to results of a retrospective study published in Journal of the National Cancer Institute.

An FDA panel today supported approval of olaparib as maintenance treatment for adults with deleterious or suspected deleterious germline BRCA-mutated metastatic pancreatic cancer.

A combination of atezolizumab and bevacizumab conferred statistically significant and clinically meaningful improvements in PFS and OS compared with sorafenib among patients with unresectable hepatocellular carcinoma, according to results of the randomized phase 3 IMbrave150 study presented at European Society for Medical Oncology Asia Congress.

The FDA granted priority review to pemigatinib for the treatment of patients with previously treated, locally advanced or metastatic cholangiocarcinoma and FGFR2 fusions or rearrangements, according to a press release from the agent’s manufacturer.

Omega-3 supplementation of 1 g per day did not appear to reduce the risk for colorectal cancer precursors among the average-risk U.S. population, according to results of an ancillary study of the randomized VITAL trial published in JAMA Oncology.

Rates of squamous cell carcinoma of the anus and related mortality have risen sharply over the past 15 years, according to results of a retrospective study published in Journal of the National Cancer Institute.

Laparoscopic resection conferred a long-term survival advantage compared with open hepatectomy for patients with liver metastases from colorectal cancer, according to findings from a patient-level meta-analysis published in Annals of Surgery.

Cancer incidence rates represent one key measure of progress in the fight against cancer, but they are not the only consideration. According to a special report published in The New England Journal of Medicine, concordance between incidence and mortality rates provides a more complete picture of cancer burden.