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July 10, 2023
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VIDEO: Cyto-KIK trial examines cabozantinib and cytoreductive nephrectomy

In this video, Farshid Sadeghi, MD, discussed data from the Cyto-KIK trial on renal cell carcinoma at American Urological Association Annual Meeting.

Sadeghi, a clinical assistant professor at City of Hope Phoenix, highlighted the study, which examined patients with metastatic renal cell carcinoma being treated by a combination therapy of cabozantinib (Cabometyx, Exelixis) and immunotherapy, undergoing cytoreductive nephrectomy, and subsequently resuming the combination therapy.

“For us as surgeons it’s useful to know that after stopping cabozantinib for 2 weeks, patients can be taken to the operating group,” Sadeghi said.

Reference:

  • Runcie K, et al. Assessment of surgical complications in patients with metastatic clear cell renal cell carcinoma (mccRCC) receiving perioperative cabozantinib and nivolumab on Cyto-KIK clinical trial. Presented at: American Urological Association Annual Meeting; April 28-May 1, 2023; Chicago.