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May 05, 2023
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VIDEO: IMbrave050 study a ‘huge breakthrough’ in hepatocellular carcinoma

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In this video, James Cleary, MD, PhD, a medical oncologist at Dana-Farber Cancer Institute, discussed results from the phase 3 IMbrave050 trial, presented at American Association for Cancer Research Annual Meeting.

Cleary highlighted the study, which found increased recurrence-free survival of patients with hepatocellular carcinoma treated with adjuvant therapy with atezolizumab (Tecentriq, Genentech) and bevacizumab (Avastin, Genentech) although not without its drawbacks.

“The one fly in the ointment is that there were more treatment-related deaths on the atezolizumab-bevacizumab arm,” Cleary said. “But fingers crossed, because this could really be a great gain for our patients.”