Inflammation levels linked to survival in acute myeloid leukemia
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Severe inflammation among individuals with acute myeloid leukemia limits their bodies’ ability to kill cancerous blood cells, according to study results.
Researchers correlated “iScores” — a measure of each study participant’s level of inflammation — with survival. They determined those with the highest scores died at least 4 years earlier than those with lower inflammation levels.
The results suggest the iScore system can be a complementary tool for physicians and patients to measure AML severity, according to investigators.
Healio spoke with researchers Audrey Lasry, PhD, and Bettina Nadorp, PhD, postdoctoral fellows at NYU Grossman School of Medicine and NYU Langone Health’s Perlmutter Cancer Center, about the findings and their potential implications.