10-second videos help predict relapse after hematopoietic stem cell transplantation
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Ten-second videos of white blood cell motion in the skin’s microvasculature considerably improved the ability to predict whether blood cancer would relapse after hematopoietic stem cell transplantation, according to study results.
Transplant recipients whose white blood cells on video demonstrated greater adherence levels and greater rolling along vessel walls appeared more than three times as likely to die or develop relapse than those with normal levels, Vanderbilt University Medical Center researchers found.
This approach appeared several times more predictive for relapse and death than the best available clinical predictor, according to findings presented at American Academy of Dermatology Annual Meeting and published in JAMA Dermatology.
Healio spoke with researchers Eric Tkaczyk, MD, PhD, FAAD, director of the Vanderbilt Dermatology Translational Research Clinic, and Inga Saknite, PhD, adjoint assistant professor of dermatology, about the results and their potential clinical implications.
Reference:
Saknite I, et al. JAMA Dermatol. 2022;doi:10.1001/jamadermatol.2022.0924.
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