VIDEO: "Surprising" association between CAR T-cell therapy and cytopenia
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In this video, Joshua Sasine, MD, PhD, assistant professor of medicine hematology & cellular therapy at the Samuel Oschin Cancer Center Regenerative Medicine Institute, discusses a presentation from his group at ASH on the association between CAR T-cells and the cytopenia that commonly occur after therapy.
"If you have severe or prolonged cytopenias after CAR T-cell, you have a very low chance of durable remission, whereas those patients who had a rebound of their bone marrow function, the vast majority of whom were in a durable remission after CAR T-cell for DLBCL," Sasine said.
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Tabbara N, et al. Abstract 3869. Presented at: ASH Annual Meeting and Exposition; Dec. 11-14, 2021; Atlanta.
Kim M, et al. Abstract 734. Presented at: ASH Annual Meeting and Exposition; Dec. 11-14, 2021; Atlanta.
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