Columbia University professor receives award for outstanding basic cancer research
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American Association for Cancer Research presented its AACR-GHA Clowes Award for Outstanding Basic Cancer Research to Carol L. Prives, PhD, FAACR.
Prives is Da Costa professor of biology in the department of biological sciences at Herbert and Florence Irving Institute for Cancer Dynamics at Columbia University.
The award recognizes her discovery that p53 is a DNA sequence-specific transcriptional activator that possesses novel oncogenic functions when mutated. She also is being honored for her work related to the identification of stress signal-induced regulatory mechanisms of p53 and Mdm2, as well as for identifying novel pathways by which p53 functions to suppress cell growth and promote cell death.
“Dr. Prives’ innovative, pioneering work in characterizing the behavior and function of the p53 tumor suppressor gene has contributed markedly to providing a solid foundation for a whole field of molecular cancer research,” Margaret Foti, PhD, MD (hc), CEO of AACR, said in an association-issued press release.
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