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March 07, 2021
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American Association for Cancer Research honors stem cell biology expert

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American Association for Cancer Research has recognized Hans Clevers, MD, PhD, FAACR, with the 2021 Pezcoller Foundation-AACR International Award for Extraordinary Achievement in Cancer Research.

The award honors Clevers for his contributions to regenerative cancer medicine, according to an AACR press release.

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Source: Adobe Stock.

Clevers’ research led to the development of organoids, which have applications in multiple avenues of research, including regenerative cancer medicine and testing of novel anticancer therapeutics, the release stated. His studies of the Wnt signaling pathway — mutations in which can contribute to development and progression of colon cancer — has propelled research efforts that target the pathway with novel therapeutics, according to the release.

Margaret Foti
Margaret Foti

“We are extremely proud to honor Dr. Clevers with this year’s Pezcoller Foundation-AACR International Award for Extraordinary Achievement in Cancer Research,” Margaret Foti, PhD, MD (hc), CEO of AACR, said in the release. “His pioneering research in stem cell biology, which led to the establishment of organoids as an essential model system for cancer research, has deepened our understanding of cancer’s origins and revolutionized cancer drug development for the benefit of patients around the world.”

Clevers is a professor of molecular genetics at University Medical Center in Utrecht, Netherlands, where he serves as principal investigator at Hubrecht Institute for Developmental Biology and Stem Cell Research and at Princess Máxima Center for Pediatric Oncology.

He will be presented with the award during the virtual AACR Annual Meeting, scheduled for April 10-15 and May 17-21.