October 20, 2013
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Cleveland Clinic announces top 10 medical innovations for 2014

The Cleveland Clinic has released its choices for the top 10 medical innovations that will have a major impact on improving patient care in 2014.

This list, presented at the clinic’s annual Medical Innovation Summit, includes “game changing” technologies for cancer treatment such as genome-guided solid tumor diagnostics and B-cell receptor pathway inhibitors.

Selected by a panel of physicians and scientists, Cleveland Clinic’s Top 10 Medical Innovations list was developed to share what innovations their clinical leaders feel will help shape health care in the next 12 months.

The Top 10 Medical Innovations for 2014 include:

  1. Retinal prosthesis system
  2. Genome-guided solid tumor diagnostics
  3. Responsive neurostimulator for intractable epilepsy
  4. Direct-acting antiviral oral hepatitis C drugs
  5. Perioperative decision support system
  6. Fecal microbiota transplantation
  7. Relaxin for acute heart failure
  8. Computer-assisted personalized sedation system
  9. TMAO assay: novel biomarker for the microbiome
  10. 10.  B-cell receptor pathway inhibitors

Four major criteria served as the basis for selection. To receive consideration, nominated technologies had to meet the following criteria:

  • The innovation must have significant clinical impact and offer significant patient benefit in comparison to current practices. It must also have high user-related functionality that improves health care delivery.
  • Nominated innovations must have a high probability of commercial success.
  • The innovation must be in or exiting clinical trials and be available on the market within the coming year.
  • The innovation must have significant human interest in its application or benefits, and must have the ability to visualize human impact.
The nominated innovations were first screened to confirm threshold criteria and consolidate duplicates. The Cleveland Clinic team then prepared research on each technology and presented a final list of more than 55 flourishing technologies and their data profiles to two independent panels of leading Cleveland Clinic physicians. In late August, each panel met separately to discuss, debate and vote, and then jointly voted on the combined lists.