August 17, 2009
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The best of news in cancer
I've been on an impromptu vacation this week so am just catching up with some cancer news I missed. Here's the best of it:
- Lancet published some interesting Letters to the Editor about the insulin glargine–cancer connection, arguing that there are other sides to this association to be considered.
- As I think I have pointed out before, cancer mortality rates continue to decline, and the bulk of the progress has been made in pediatric malignancies (this is, I think, a very good thing, to steal a line from Martha Stewart).
- JAMA published a prospective cohort study on aspirin use and survival after colorectal cancer, showing improved survival. But the bulk of the benefit was among patients whose tumors expressed COX-2.
- In a very well-done prospective, randomized, controlled clinical trial, a program of progressive weight lifting prevented worsened swelling of the affected limb in breast cancer survivors with lymphedema and may also prevent future exacerbations (Also read the accompanying editorial.).
- Cetuximab has been found to not be cost-effective relative to benefit among KRAS wild-type patients.