December 13, 2010
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A few great cancer stories have caught my eye recently:
- Adjuvant TAC is superior to FAC for disease free survival for node negative breast cancer, but not overall survival. Given that very few US oncologists use FAC, I'm not sure this will make a major change in current practice, however. But, it is another good option in the breast cancer arsenal. ( article hereHemOnc Today).
For those of you who regularly treat breast cancer, do you think you would change your preferred adjuvant therapy based on this study? - In what seems to me to be an unexpected finding, low dose aspirin use *helped* the performance of two types of iFOBT cards, by increasing the sensitivity of the test. I think iFOBT is way underused for those patients who can't afford a colonoscopy as their sole way of screening for colon cancer (think of all those uninsured or underinsured patients, or those who can't take a day and half off work for the prep and procedure), and this evidence shows us ways to improve the accuracy of iFOBT further.
- And, file this one under Really Simple Things That Really Do Work: Aspirin may be even more helpful in preventing cancer than originally thought. Think of the difference that could be made if we all did the simple things we know are helpful to prevent cancer — exercise, take an aspirin a day, don't smoke, drink only in moderation, maintain a healthy weight — the effects would be mind boggling and a whole lot cheaper than the newest, greatest, expensive chemotherapy drug or radiation approach.