Microneedling with TCA superior to carbon dioxide laser resurfacing for hyperpigmentation
Click Here to Manage Email Alerts
Microneedling combined with 10% trichloroacetic acid peels improved and maintained hyperpigmentation more than carbon dioxide laser resurfacing alone, according to a study presented at the American Academy of Dermatology virtual meeting.
“Infraorbital dark circles are one of the major cosmetic concerns, which is defined as pigmentation under the eyes,” Banu Farabi, MD, of Ankara University School of Medicine, told Healio Dermatology. “The idea behind choosing microneedling plus 10% trichloroacetic acid was, these modalities are cheaper compared to other options and proven to be effective in other pigmentary disorders such as melasma.”
In the clinical trial, 62 subjects with infraorbital dark circles were studied. They received either a microneedling procedure combined with a topical application of 10% trichloroacetic acid (TCA) solution to the area or a carbon dioxide laser resurfacing procedure.
Blinded-investigator assessment results showed the laser resurfacing procedure did not yield significant improvements at day 90, while there was significant improvement with combination microneedling and 10% TCA at day 90 (P = .012) with maintenance through day 180 (P = .002).
“Microneedling and TCA combination is easy to apply and has a good adverse event profile with high efficacy, which is feasible for both patients and physicians ... in the treatment of infraorbital pigmentation,” Farabi said. “With this study, we were able to prove superiority of combination and less adverse events compared to carbon dioxide laser.”
Collapse
Farabi B, et al. Comparing the efficacy of combination of microneedling and 10% trichloroacetic acid peels versus carbon dioxide laser resurfacing in the treatment of infraorbital dark circles. Presented at: AAD VMX; June 12-14, 2020 (virtual meeting).
Read more about
Click Here to Manage Email Alerts