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August 01, 2021
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Catheter ablation may benefit patients with atrial flutter but no AF

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Atrial flutter catheter ablation in patients without a history of atrial fibrillation reduced risk for death, stroke, HF and AF compared with medical management, according to an abstract presented at Heart Rhythm 2021.

Dony Yugo, from the Heart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan, and colleagues wrote in an abstract that they conducted the study because “the data regarding the long-term efficacy of cavotricuspid isthmus dependent atrial flutter (AFL) ablation in terms of mortality and cardiovascular risk in AFL patients without AF history was still unclear.”

Cardiologist _192016818
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The researchers analyzed the data of 3,784 patients diagnosed with AFL without a previous AF diagnosis. Outcomes of interest included total deaths, cardiac deaths, HF and AF admissions. Data were propensity matched for age, sex, comorbidities and medications.

Compared with those who were managed medically, patients who received AFL ablation and future AF ablation had reduced risk for all-cause death (HR = 0.68; 95% CI, 0.62-0.74; P < .001), cardiac death (HR = 0.78; 95% CI, 0.67-0.91, P = .001), HF (HR = 0.84; 95% CI, 0.75-0.95, P = .01) and AF admissions (HR = 0.83; 95% CI, 0.76-0.92, P < .001). Receiving only AFL ablation still lowered risk for all-cause death (HR = 0.65; 95% CI, 0.58-0.72, P < .001), cardiac death (HR = 0.77; 95% CI, 0.64-0.92, P = .003) and HF admissions (HR = 0.83; 95% CI, 0.72-0.96, P = .01) compared with medical management.

“Survival curve analysis showed that patients who had AFL ablation had a significantly better outcome in terms of total deaths, cardiovascular deaths, HF admissions and AF admissions compared to medically treated patients,” Yugo and colleagues wrote in the abstract.