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April 20, 2021
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Among stroke survivors who smoke, e-cigarette users more likely to quit

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Nearly 14% of active smokers who survived a stroke use e-cigarettes, and those users were more inclined than e-cigarette nonusers to try to quit smoking within the past year, according to a research letter published in JAMA Neurology.

“E-cigarette use is increasingly common, so we were motivated to understand the extent to which e-cigarette use is an unaddressed risk factor among stroke survivors. We also wondered whether stroke survivors are using e-cigarettes to help them quit smoking regular cigarettes,” Neal S. Parikh, MD, MS, assistant professor of neurology and neuroscience at Weill Cornell Medicine, told Healio.

Graphical depiction of source quote presented in the article
Neal S. Parikh, MD, MS, assistant professor of neurology and neuroscience at Weill Cornell Medicine.

“The key take-home messages are that stroke survivors frequently use both regular and e-cigarettes, so their doctors need to ask specifically about e-cigarette use,” Parikh said.

In a cross-sectional analysis, researchers used pooled data from the 2016-2018 CDC Behavioral Risk Factor Surveillance System surveys.

The researchers analyzed a cohort of 6,867,786 stroke survivors (mean age, 60 years), of whom 23.6% (95% CI, 22.7-24.5) were active smokers.

Among actively smoking stroke survivors, 49.2% were women, 22.2% lived in the Stroke Belt (Alabama, Arkansas, Georgia, Indiana, Kentucky, Louisiana, Mississippi, North Carolina, South Carolina, Tennessee and Virginia) and 65.7% were white, the researchers wrote.

Researchers observed that diabetes was present in 27.9% (95% CI, 25.9-29.9) and hypertension in 65.6% (95% CI, 61.9-69.2) of stroke survivors.

The frequency of active e-cigarette use was 13.5% (95% CI, 11.8-15.3), and among active smokers, 62.3% (95% CI, 60.2-64.4) reported that they tried to quit smoking within the past year, according to the researchers.

Compared with smokers who did not use e-cigarettes, e-cigarette users were more likely to have attempted to quit cigarette smoking (users, 73%; 95% CI, 67.2-78.9; nonusers, 60.7%; 95% CI, 58.5-62.9; OR = 1.63; 95% CI, 1.21-2.19).

“Doctors should ask, ‘Are you using e-cigarettes to help you quit smoking regular cigarettes?’ and then provide patients with guideline-recommended smoking-cessation resources and should refer their patients with persistent smoking to tobacco treatment specialists who can provide dedicated attention,” Parikh told Healio.

For more information:

Neal S. Parikh, MD, MS, can be reached at nsp2001@med.cornell.edu.