February 27, 2019
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Lesion morphology predicts complications in balloon pulmonary angioplasty for CTEPH

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Lesion morphology was the only independent predictor of complications in balloon pulmonary angioplasty procedures to treat chronic thromboembolic pulmonary hypertension, researchers reported.

Via angiography and noncontrast CT, the researchers analyzed 879 lesions from 30 patients (mean age, 68 years; 60% women) with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) who underwent balloon pulmonary angioplasty.

Of the 123 complications detected, 99.2% were determined to be associated with the balloon pulmonary angioplasty procedure, Nobutaka Ikeda, MD, PhD, from the division of cardiovascular medicine at Toho University Ohashi Medical Center in Tokyo, and colleagues wrote.

When the researchers performed a multivariable analysis, they determined that the only independent predictor of procedure-related complications was occlusive lesions (adjusted OR = 5.83; 95% CI, 1.94-17.47) and found that hemodynamic parameters were not predictors.

“CT scan images after [balloon pulmonary angioplasty] were useful to identify bleeding complications and to predict hemoptysis,” Ikeda and colleagues wrote. “Our study is the first report to present a detailed analysis of lesion morphologies and complications.” – by Erik Swain

Disclosures: The authors report no relevant financial disclosures.