New-onset AF similar after TAVR, surgical AVR

CHICAGO — Patients who underwent transcatheter aortic valve replacement had a comparable incidence of new-onset atrial fibrillation compared with those who underwent surgical AVR, according to data presented at the American Heart Association Scientific Sessions.

Rajat Kalra, MD, chief fellow of cardiology at University of Minnesota in Minneapolis, and colleagues analyzed data from patients who underwent TAVR (n = 32,805; mean age, 81 years; 53% men) or isolated surgical AVR (n = 98,525; mean age, 68 years; 61% men) from the National Inpatient Sample from 2012 to 2014.

The primary outcome of interest was the occurrence of new-onset AF. Of the patients in the study, 50.9% in the TAVR group and 49.8% in the surgical AVR group had new-onset AF.

In the TAVR group, compared with patients without new-onset AF, those who were diagnosed with the condition had a higher rate of in-hospital mortality (4.2% vs. 2.2%). This difference was also seen in patients who underwent surgical AVR (new-onset AF, 2.1%; no AF, 1.1%).

After propensity-score matching, patients who underwent TAVR and had new-onset AF had increased risk for in-hospital mortality compared with patients who had TAVR without new-onset AF (OR = 1.84; 95% CI, 1.6-2.12). Those who underwent surgical AVR and had new-onset AF also had an increased risk for in-hospital mortality compared with those without AF (OR = 1.4; 95% CI, 1.24-1.58). – by Darlene Dobkowski

Reference:

Kalra R, et al. Poster Mo1288. Presented at: American Heart Association Scientific Sessions; Nov. 10-12, 2018; Chicago.

Disclosures: The authors report no relevant financial disclosures.