Issue: July 2018
June 06, 2018
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Preoperative walk distance predicts cognitive dysfunction after cardiac surgery

Issue: July 2018

Preoperative 6-minute walk distance identified patients with cognitive dysfunction after cardiac surgery, researchers reported in the Annals of Thoracic Surgery.

Kazuhiro Hayashi, PT, MS, from Nagoya University Hospital in Japan, and colleagues analyzed 181 patients (mean age, 71 years) who underwent nonemergency cardiac surgery at a single center between March 2014 and August 2015 to determine whether low preoperative 6-minute walk distance was related to postoperative cognitive dysfunction.

Patients were stratified by whether they had postoperative cognitive dysfunction, defined as a decline of at least 2 points on the Mini-Mental State Examination score.

According to the researchers, 28% of patients in the cohort had postoperative cognitive dysfunction.

Median preoperative 6-minute walk distance was 400 m in those with postoperative cognitive dysfunction and 450 m in those without it, Hayashi and colleagues wrote.

In multivariable analyses, the researchers identified old age, high Mini-Mental State Examination score, low 6-minute walk distance and long ICU stay as independent predictors of postoperative cognitive dysfunction.

The OR of each 50-m increase in preoperative 6-minute walk distance for postoperative cognitive dysfunction was 0.807 (95% CI, 0.69-0.943), Hayashi and colleagues wrote.

“This study indicates that the easy and inexpensive 6-minute walk distance is a valuable assessment for identifying patients at a high risk for [postoperative cognitive dysfunction],” Hayashi said in a press release. “If we are able to identify patients who are at risk for [postoperative cognitive dysfunction], we can provide early treatment and encourage them to better understand the dysfunction.” – by Erik Swain

Disclosures: The authors report no relevant financial disclosures.