This article is more than 5 years old. Information may no longer be current.
Outcomes differ in patients with acute HF based on systolic BP, clinical profile
Click Here to Manage Email Alerts
Adverse outcomes differed in patients with acute HF based on systolic BP and clinical profile at admission, although variances were reduced up to 6 months after discharge, according to a study in the European Journal of Heart Failure.
Ovidiu Chioncel, MD, PhD, a professor at the Institute of Emergency for Cardiovascular Diseases at the University of Medicine Carol Davila in Bucharest, Romania, and colleagues analyzed data from the European Society of Cardiology Heart Failure Long-Term Registry of 6,629 patients (63% men) aged 18 years and older who were admitted for acute HF. Patients in the registry included those with cardiogenic shock (2.9%), pulmonary edema (13.2%), hypertensive HF (4.8%), decompensated HF (61.1%), right HF (3.5%) and ACS (14.4%). Follow-up visit occurred 12 months after entry visit.
All-cause mortality was the in-hospital outcome. One-year outcomes were defined as 1-year HF readmissions, 1-year mortality, and 1-year death or HF readmission.
Patients with cardiogenic shock had the highest rates of in-hospital all-cause mortality (36.1%), and those with hypertensive HF had the lowest rates (1.8%). One-year HF hospitalization occurred in 25.9% of the patient population, and the 1-year mortality rate was 26.7%. Within the overall population, CV deaths accounted for 57.2% of all deaths.
One-year all-cause death rates were 54% in those with cardiogenic shock, 28.1% in those with pulmonary edema, 12.8% in those with hypertensive HF, 27.2% in those with decompensated HF, 20.6% in those with ACS and 33.9% in those with right HF (P < .0001).
One-year mortality rates were 34.8% in patients with systolic BP less than 85 mm Hg, 29% in those with systolic BP between 85 mm Hg and 110 mm Hg, 21.2% in patients between 110 mm Hg and 140 mm Hg, and 17.4% of patients with systolic BP greater than 140 mm Hg (P < .0001).
However, among patients who survived at least 6 months, systolic BP and clinical profile at admission were not as strong factors in 1-year outcomes, the researchers wrote.
“The [ESC Heart Failure Long-Term] Registry demonstrates the importance of systematic characterization of [acute] HF patients during their in-hospital course,” Chioncel and colleagues wrote. “Classifying [acute] HF patients on the basis of clinical relevant data may mediate improvements in quality of care and outcomes.” – by Darlene Dobkowski
Disclosure: Chioncel reports receiving grants from Novartis, Servier and Vifor. Please see the full study for a list of the other researchers’ relevant financial disclosures.
Click Here to Manage Email Alerts