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Cardiology Today’s top 5 articles posted in December
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Cardiology Today compiled a list of the top 5 stories posted to Healio.com/Cardiology in December.
This month, Cardiology Today readers were most interested in a report released from the American College of Cardiology and American Heart Association regarding sudden cardiac death prevention, adverse events caused by off-label nonvitamin K antagonist oral anticoagulants, the NIH’s selection of the inaugural CEO of the NIH Clinical Center, the link between moderate alcohol consumption and AF risk, genetic variants effect on CV events and diabetes, and much more.
ACC, AHA publish 10 measures for sudden cardiac death prevention
A task force of the ACC and AHA released a report with 10 quality and performance measures that can help prevent sudden cardiac death.
“This is the first comprehensive measure set in the area of sudden cardiac death prevention,” Sana Al-Khatib, MD, MHS, FACC, FAHA, FHRS, professor of medicine at Duke University and co-chair of the writing committee, said in a press release. “Our vision is that these measures will be developed, tested and implemented in clinical practice and that implementation will improve patient care and outcomes.”
Off-label nonvitamin K antagonist oral anticoagulant dosing linked to adverse events
Approximately one in eight patients in the United States receive dosing of nonvitamin K antagonist oral anticoagulants that is inconsistent with the FDA-approved recommendation on the label, according to data published in the Journal of the American College of Cardiology.
Researchers determined the associations between off-label dose therapy and clinical outcomes in community practice among patients with atrial fibrillation from the ORBIT-AF II registry.
NIH taps cardiologist to lead largest US hospital devoted to clinical research
The NIH announced that it selected retired Army Maj. Gen. James K. Gilman, MD, to serve as the inaugural CEO of the NIH Clinical Center, the largest hospital dedicated to clinical research in the United States.
Gilman’s career includes a stint as chief of cardiology at Brooke Army Medical Center at Fort Sam Houston in San Antonio, in which he was responsible for training cardiology fellows, according to a press release from the NIH.
Review: Moderate but regular alcohol consumption can raise risk for AF
People who drink a moderate level of alcohol on a regular basis appear to be at increased risk for atrial fibrillation, according to a review published in the Journal of the American College of Cardiology.
Although moderate consumption of alcohol has been associated with reduced risk for CAD, the same is not true for AF, according to the researchers.
Two genetic variants may reduce CV event risk, increase diabetes risk
Variants of the PCSK9 and HMGCR genes linked to lower LDL were associated with protection from CV events and increased risk for diabetes in certain populations, according to findings published in The New England Journal of Medicine.
The researchers compared the effects of lower LDL levels conferred by the variants of PCSK9 and HMGCR on risk for CV events and diabetes. They wrote that PCSK9 variants mimic the effects of PCSK9 inhibitors, and the HMGCR variants mimic the effects of statins.