Issue: February 2016
January 06, 2016
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CDC: After years of decline, US HF-related mortality rising again

Issue: February 2016
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The U.S. age-adjusted HF-related death rate fell from 2000 to 2012 but rose from 2012 to 2014, according to a report from the CDC’s National Center for Health Statistics.

Perspective from Erin Coglianese, MD

The rate of deaths for which HF was the underlying or a contributing cause was higher in non-Hispanic blacks than in other races, and over time the underlying cause of HF-related death was less likely to be CHD, Hanyu Ni, PhD, and Jiaquan Xu, MD, both from the division of vital statistics of the CDC’s National Center for Health Statistics, wrote in the report.

According to the report, the age-adjusted rate for HF-related deaths fell from 105.4 per 100,000 people in 2000 to 81.4 per 100,000 people in 2012 (P < .05), but rose to 84 per 100,000 people in 2014 (P < .05). The crude rate of HF-related deaths fell from 103.1 per 100,000 people in 2000 to 89.5 per 100,000 people in 2009 (P < .05), then rose to 96.9 per 100,000 in 2014 (P < .05).

Breakdown by race

The age-adjusted rate for HF-related death was higher in non-Hispanic blacks than in non-Hispanic whites and Hispanics from 2000 to 2014, with the 2014 rates being 91.5 per 100,000 people for non-Hispanic blacks, 87.3 per 100,000 people for non-Hispanic whites and 53.3 per 100,000 people for Hispanics (P < .05), according to the report.

The age-adjusted HF-related death rate fell 20% for non-Hispanic blacks and 22% for non-Hispanic whites between 2000 and 2012, but rose 4% for both between 2012 and 2014 (P < .05 for all), whereas it fell 27% for Hispanics from 2000 to 2014, Ni and Xu wrote.

In all age groups — 45 to 64 years, 65 to 74 years, 75 to 84 years and 85 years or older — the rate of HF-related death declined from 2000 to 2012 but rose from 2012 to 2014 (P < .05), with the death rate increasing with age (P < .05), according to the report.

The HF-related death rate was higher for men than for women in all age groups (P < .05), and the gap between men and women increased over time, the authors wrote.

Between 2000 and 2014, the percentage of HF-related deaths occurring at a hospital declined 30%, whereas the percentage at a descendant’s home increased 51%, the percentage at a nursing home or long-term care facility declined 11% and the percentage occurring elsewhere, such as an outpatient clinic or hospice facility, increased 74%, the report stated.

Less related to CHD

CHD was the underlying cause of HF-related death 34.9% of the time in 2000 but only 23.9% of the time in 2014 (P < .05), an overall decrease of 32%, the authors wrote. The percentage of other CVD being the underlying cause rose from 35.6% in 2000 to 41.2% in 2014 and the percentage of non-CVDs — including cancer, diabetes, lower respiratory diseases and kidney disease — being the underlying cause rose from 29.4% in 2000 to 34.9% in 2015 (P < .05 for both), they wrote.

“The shift in the distribution of the causes of death toward less ischemic heart disease is consistent with the results of a community-based study on [HF],” Ni and Xu wrote. “This finding is important for [HF] management approaches.” – by Erik Swain

Disclosure: Ni and Xu are employees of the CDC.