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Peripheral vascular intervention found effective in women
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Percutaneous peripheral vascular intervention demonstrated encouraging procedural and technical success rates in a cohort of women with peripheral arterial disease, according to recent findings.
The aim of the study was to determine whether percutaneous peripheral vascular intervention outcomes were different among men and women.
The analysis included 12,379 patients, 41% of whom were women. Eligible participants underwent lower extremity percutaneous peripheral vascular intervention between 2004 and 2009 at 16 hospitals participating in the Blue Cross Blue Shield of Michigan Cardiovascular Consortium PVI registry.
The women in the cohort were more likely to be older, have multilevel disease and critical limb ischemia. Vascular complications, transfusions and embolism occurred more frequently in women, according to results of a propensity-matched analysis.
In-hospital mortality, MI and stroke/transient ischemic attack rates were similar among women and men.
Technical success rates were 91.2% for women and 89.1% for men (P=.014). However, higher complication rates among women resulted in similar overall procedural success rates between the two groups (women, 79.7% vs. men, 81.6%; P=.08).
“Females represent a significant proportion of patients undergoing [lower extremity peripheral vascular intervention], have more severe and complex disease process, and are at increased risk for adverse outcomes,” the researchers concluded, adding that the procedural success rates demonstrated in this study make this approach a viable alternative in women with lower extremity PAD.
Disclosure: The researchers report relevant financial disclosures with Blue Cross Blue Shield of Michigan, McKesson, Medtronic Cardiovascular and Pfizer.
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