This article is more than 5 years old. Information may no longer be current.

Women face higher mortality risk after PCI for STEMI

Add topic to email alerts

Receive an email when new articles are posted on

Please provide your email address to receive an email when new articles are posted on .

Subscribe

Added to email alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

Back to Healio

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Back to Healio

LAS VEGAS — At 30 days, women with STEMI who underwent primary PCI had a mortality rate that was more than double that of men, according to data presented at the Society for Cardiovascular Angiography and Interventions Scientific Sessions.

Francesco Tomassini, MD, of Infermi Hospital, Rivoli, Italy, and colleagues analyzed 1,251 patients (313 women) who underwent primary PCI within 12 hours of STEMI at their institution between September 2001 and June 2010. They compared 30-day mortality rates and a number of clinical and procedural characteristics between men and women.

The 30-day mortality rate was 11.8% for women vs. 5.5% for men (P<.0001). After propensity adjustment, women remained at an elevated risk for 30-day mortality compared with men (OR=0.56; 95% CI, 0.34-0.93).

Francesco Tomassini

The risk for bleeding at 30 days was also significantly higher among women: 4.5% vs. 1.4% for men (P=.002).

“Our data suggest the hypothesis that biological gender-related differences could, in part, explain these findings,” Tomassini and colleagues wrote in the abstract.

According to other results, women had a higher symptom-to-balloon time (291 minutes vs. 238.5 minutes; P<.0001) and lower left ventricular ejection fraction (46.8% vs. 48.5%; P=.007) compared with men. Further, the researchers observed, women were less likely compared with men to be treated with glycoprotein IIb/IIIa inhibitors (76% vs. 85.8%; P<.0001), thrombus aspiration devices (42.4% vs. 57.3%; P<.0001) or stents (81.1% vs. 88.4%; P=.002).

Compared with men, women were less likely to smoke (24.9% vs. 75.7%; P<.0001), less likely to have left main disease (3.8% vs. 5.1%; P<.0001), more likely to have diabetes (32.4% vs. 24%; P<.0001) and more likely to have hypertension (77.3% vs. 65.8%; P<.0001). – by Erik Swain

For more information:

Tomassini F. Abstract A-021. Presented at: the Society for Cardiovascular Angiography and Interventions Scientific Sessions; May 28-31, 2014; Las Vegas.

Disclosure: Tomassini reports no relevant financial disclosures.