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Insomnia increases risk for ACS

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ATLANTA — Patients with insomnia are significantly more likely than those without insomnia to develop ACS, according to study results presented at Obesity Week.

For a longitudinal study, researchers evaluated data on 22,677 patients diagnosed with insomnia without prior ACS diagnosis, along with 68,031 randomly selected, sex-matched controls without insomnia. All data were collected from the Taiwan National Health Insurance Research Database. Incidence of hospitalization for ACS between 2002 and 2009 was compared between the two groups.

“While the relationships between insomnia and obesity have been widely studied, limited research has investigated the effects of insomnia on ACS among [the] general population,” researchers wrote in the study abstract.

Hospitalization due to ACS occurred more frequently in the insomniac group, with 15.7 cases per 1,000 person-years vs. 8.86 per 1,000 person-years among those without insomnia (P<.001). Patients with insomnia also were significantly more likely to have depression, diabetes, hyperlipidemia and hypertension compared with those without insomnia (P<.001).

Researchers calculated a HR of 1.77 (95% CI, 1.48-2.12) for the development of ACS among those with insomnia vs. those without, after adjustment for factors such as age, sex, socioeconomic status and the presence of depression, diabetes, hyperlipidemia and hypertension.

“Insomnia can predict ACS,” researcher Ya-Wen Hsu, PhD, assistant professor at Chia Nan University in Taiwan, told Cardiology Today. “Most of the time, insomnia has been conceived of as a side symptom … people pay less attention to [it]. This brings attention [to] insomnia as crucial for CVD prediction.” – by Adam Taliercio

For more information:

Hsu YW. Abstract T-286-P. Presented at: Obesity Week 2013; Nov. 11-16, 2013; Atlanta.

Disclosure: Hsu reports no relevant financial disclosures.