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TIMI risk score predicted mortality in patients treated for STEMI
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Among patients who underwent primary PCI for STEMI, results from a recent study have suggested that the TIMI risk score may predict mortality over the long and short term.
Researchers investigated this correlation by collecting data from 3,609 consecutive patients with STEMI who underwent primary PCI in a high-volume center in the Netherlands from 2000 to 2007. The median follow-up duration was 1,384 days.
According to study results, higher TIMI scores were associated with significantly higher mortality at short- and long-term follow-up (P<.001 for both). Age and Killip class IV at presentation significantly predicted short- and long-term mortality.
Patients with an anterior MI, heart frequency of >100 beats per minute or systolic BP <100 mm Hg had a worse short-term prognosis compared with patients who did not experience those variables. However, differences in long-term mortality did not reach statistical significance.
A history of diabetes, hypertension and weight had long-term prognostic value from 30 days up to 4 years, whereas time to primary PCI did not have any prognostic value.
Researchers reported that only one previous study had validated the long-term predictive value of the TIMI risk score in a primary PCI setting.
“While the guidelines emphasize the importance of early risk stratification in order to identify patients in which early interventions can improve outcomes, identifying patients at the highest risk of longer-term mortality can potentially provide new therapeutic targets after [primary] PCI,” they wrote.
Disclosure: The researchers report no relevant financial disclosures.
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