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OCT Comparable to IVUS in Identifying Coronary Stenoses
Among patients with intermediate coronary stenoses, optical coherence tomography was associated with similar diagnostic accuracy when compared with IVUS, but had a slightly better assessment of small vessels, according to a study published in the Journal of the American College of Cardiology.
In the study, 56 patients with 61 stenoses with intermediate angiographic severity (40%-70% diameter stenosis) determined by quantitative coronary angiography were prospectively included. Researchers performed imaging with OCT in all cases of stenosis and concomitant IVUS imaging in 47 stenoses.
Overall, OCT was found to have a moderate diagnostic accuracy (area under the curve [AUC]: 0.74). Among patients with simultaneous IVUS and OCT imaging, OCT had similar diagnostic accuracy compared with IVUS (OCT AUC: 0.70 vs. IVUS AUC: 0.63; P=.19). Sensitivity/specificity for OCT was 82%/63% for an optimal cutoff value of 1.95 mm², whereas for IVUS it was 67%/65% with an optimal cutoff of 2.36 mm².
Furthermore, in a subgroup analysis of small vessels with a reference diameter of less than 3 mm (OCT n=49; IVUS n=38), OCT was better at identifying functionally significant stenoses compared with IVUS (OCT AUC: 0.77 vs. IVUS AUC: 0.63; P=.04).
For more information:
Gonzalo N. J Am Coll Cardiol. 2012;59:1080-1089.
Perspective
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