January 01, 2012
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Suboptimal Transfer Times Reported for Most Patients Needing PCI

Herrin J. Arch Intern Med.2011;171:1879-1886.
Redberg R. Arch Intern Med. 2011;doi:10.1001/archinternmed.2011.566.

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The door-in to door-out time for patients with STEMI requiring transfer to another hospital for PCI rarely met the recommended 30 minutes, according to a study published in the Archives of Internal Medicine.

The study included time-to-transfer data developed by CMS on patients (n=13,776) with STEMI who presented to EDs in 1,034 hospitals and required transfer for PCI. They defined door-in to door-out (DIDO) time as the time from patient presentation to patient discharge from the transferring hospital.

Results indicated only 9.7% of patients had a DIDO time within the recommended 30 minutes, while the time exceeded 90 minutes in 31% of cases. After multivariable analysis, times to transfer were longer for women, blacks and those at least 75 years of age. Researchers also found that only 1.3% of hospitals met the recommended DIDO time of 30 minutes or less, with the median DIDO time for all hospitals of 68 minutes.

Rita F. Redberg
Rita F. Redberg

During their analysis, the researchers reported that many patients benefited from fibrinolytic therapy after transfer vs. primary PCI. As a result, Rita F. Redberg, MD, MSc, professor of medicine, University of California, San Francisco, and author of an accompanying editorial, said physicians should reconsider treatment strategies.

“For low- and intermediate-risk patients, there is no mortality advantage to primary PCI over thrombolytic therapy,” she wrote. “Even for high-risk patients with STEMI, the mortality benefit of primary PCI is frequently lost due to routine delays of 1 to 3 hours by transfer. It is time to reconsider transferring patients with STEMI for primary PCI. Timely reperfusion by thrombolytics, not late primary PCI via transfer, will save lives.”

Disclosure: Dr. Redberg reports no relevant financial disclosures.