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Risk for CAD increased as alcohol consumption increased in Chinese men
Zhou X. Am J Cardiol. 2010;106:1101-1103.
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Moderate-to-heavy alcohol consumption increased the risk for coronary artery disease in Chinese men, according to researchers from The Second Affiliated Hospital of Soochow University in Suzhou, People’s Republic of China.
Although many studies have shown that light-to-moderate alcohol consumption appears to protect against CAD, this has not been studied in Chinese men. The researchers conducted a case-control study to evaluate the relationship between alcohol consumption and CAD detected by angiograph.
The study included 1,476 men aged 36 to 84 years who underwent coronary arteriography. The researchers obtained alcohol consumption information using a questionnaire. The men were categorized as nondrinkers, fewer than one drink per week; light drinkers, one to six drinks per week; moderate drinkers, seven to 13 drinks per week; or heavy drinkers, more than 13 drinks per week. The researchers also determined the men’s physical activity level, weight, height, BMI, cholesterol, triglyceride levels, BP and fasting blood glucose.
They reported that age, obesity, hypertension, diabetes mellitus, hyperlipidemia, smoking and physical inactivity were confirmed risk factors for CAD. After adjusting for these factors, they found that the risk for CAD increased with increasing alcohol intake. The adjusted ORs were 1.16 for light drinkers, 1.78 for moderate drinkers and 2.18 for heavy drinkers. They also found that CAD increased as drinking frequency increased, and as the duration of drinking increased.
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