This article is more than 5 years old. Information may no longer be current.

POPE

Post Operative Pericardial Effusion

Issue: March 2010

Add topic to email alerts

Receive an email when new articles are posted on

Please provide your email address to receive an email when new articles are posted on .

Subscribe

Added to email alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

Back to Healio

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Back to Healio

Trial was conducted to assess effects of the NSAID diclofenac on size of postoperative pericardial effusion.

Design: randomized, double blind
Patients: 196
Centers: multicenter
Country: France

RESULTS: The mean change for pericardial effusion from baseline was –1.08 grades in the placebo group vs. –1.36 in the diclofenac group (P=.11). Diclofenac did not modify the secondary study endpoint of tamponade frequency (P=.49). The mean change in pericardial effusion width was –4.8 mm in the placebo group vs. –6.7 mm in the diclofenac group, with a –1.92-mm mean difference between groups (P=.07).

Published in: Ann Intern Med. 2010;152:137-143.

Click here to read more about the POPE trial.