Issue: June 2011
June 01, 2011
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Pediatric cardiomyopathy found common in pediatric arrhythmia hospitalizations

Issue: June 2011
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Heart Rhythm Society 32nd Annual Scientific Sessions

SAN FRANCISCO – Children admitted to the hospital with arrhythmias were frequently found to have pediatric cardiomyopathy compared with other diagnoses, according to results presented at the Heart Rhythm Society’s 32nd Annual Scientific Sessions.

Researchers for the study examined inpatient admissions for pediatric cardiomyopathy, which included data from 3,739 hospitals in the Healthcare Cost and Utilization Project (HCUP) Kids’ Inpatient Database. They also looked at cardiac arrhythmias and other comorbidities. Data were taken from the latest year available, which was 2006.

According to the study results, there were 8,008 (95% CI, 7,051-8,966) pediatric cardiomyopathy-related admissions in 2006. Tachyarrhythmia (9.2%) and bradyarrhythmia (2.8%) were found to be more prevalent in patients with pediatric cardiomyopathy (OR=105.4; 95% CI, 91.7-121.2) vs. those without the condition (OR=50.4; 95% CI, 41-62). Supraventricular tachyarrhythmia was reported in 4.2% (OR=68.4; 95% CI, 56.8-82.4) of patients, and ventricular tachyarrhythmia in 6% of the patients (OR=130.4; 95% CI, 97.2-175). Ventricular tachyarrhythmia was associated with an increased need for ventricular assist device support in patients with pediatric cardiomyopathy (OR=3; 95% CI, 1.4-6.3).

Multivariable analysis revealed that ventricular tachyarrhythmia (P<.001), but not supraventricular tachyarrhythmia, was an independent predictor of in-hospital mortality, even when controlling for comorbidities such as sepsis, acute renal failure, respiratory failure, stroke and seizures. Both ventricular tachyarrhythmia (P<.001) and bradyarrhythmia (P=.04) were linked with increased length of hospital stay. Patients with ventricular tachyarrhythmia also had higher costs ($54,776 vs. $33,855, P<.001) than those without it; the same applied for those with ventricular bradyarrhythmia ($53,594 vs. $34,566, P<.001).

“In this large study of pediatric hospitalization, cardiac arrhythmias were found to be significantly more prevalent in patients admitted with pediatric cardiomyopathy than other diagnoses,” the researcher wrote in an abstract. “Ventricular tachyarrhythmia was an independent predictor of in-hospital death, and both ventricular tachyarrhythmia and bradyarrhythmias were associated with increased length of hospital stay and inpatient costs.”

For more information:

  • Srinivasan C. Abstract PO1-94. Presented at: Heart Rhythm Society 32nd Annual Scientific Sessions; May 4-7, 2011; San Francisco.
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