Weight Loss

Adults with obesity who continued once-weekly semaglutide therapy beyond 20 weeks saw continued weight loss or weight maintenance compared with adults who were switched to placebo, data from the STEP 4 study show.

Weight loss after diagnosis of HER2-positive early breast cancer appeared associated with poorer survival outcomes, according to study results published in Journal of the National Comprehensive Cancer Network.

Food insecurity appeared to reduce the effectiveness of a high-intensity, lifestyle-based behavioral weight loss intervention, researchers wrote in Annals of Internal Medicine

The AGA Institute Clinical Practice Updates Committee and the Governing Board published evidence-based intervention advice for lifestyle modifications for treating nonalcoholic fatty liver disease in Gastroenterology.

A recent pilot study showed that time-restricted eating, a weight management strategy in which food is consumed in a set time period, was as good as more complex weight loss interventions.

Adults with obesity assigned the GLP-1 receptor agonist semaglutide experienced substantial weight loss compared with placebo, with more than half of participants losing 15% of body weight, according to data from the STEP 1 study.

During a follow-up of 39 months, 32% of overweight or obese patients with nonalcoholic fatty liver disease achieved 5% or greater weight loss, according to results published in Clinical Gastroenterology and Hepatology.

A 24-month lifestyle intervention provided in the primary care setting by health coaches improved cardiometabolic risk factors among patients with obesity compared with usual care alone, according to data published in Circulation.

Body weight loss may predict poor outcomes among patients with metastatic gastric or gastroesophageal junction cancer receiving third-line or later treatment, according to study results presented at Gastrointestinal Cancers Symposium.

Weight loss, intensive treatment of diabetes or prediabetic states and coffee or tea consumption may decrease the risk for alcohol-related cirrhosis, according to a study published in the American Journal of Gastroenterology.